Summary

The research team at the Laboratory of Regulatory Genomics seeks to uncover the underlying causes of aging-related diseases by decoding the regulatory genome. A core principle of their work is the need for a system-level understanding of gene regulatory circuits to identify causal genetic and molecular mechanisms in human diseases. To achieve this, they developed innovative strategies like Open4Gene and the Genetic Scorecard to prioritize specific regulatory variants. Furthermore, the study has successfully identified the convergence of coding and regulatory variants within genetic loci linked to kidney disease. These advances provide a vital framework for deciphering the complex interactions shaping modern health and longevity.

Title

Liu Lab

Description

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Keywords

research, aging, welcome, human, genetics, postdoctoral, associate, positions, disease, joining, university, genome, diseases, single, cell, variants, rochester

NS Lookup

A 185.199.108.153, A 185.199.109.153, A 185.199.110.153, A 185.199.111.153

Dates

Created 2026-03-14

Updated 2026-03-14

Summarized 2026-03-20