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domain	apostlelab.com
summary	Summary: - Key Members: The management team at Apostle Labs consists of former members of the clinical trial teams for Sofosbuvir (marketed as Sovaldi), owned by Gilead Sciences (NASDAQ: GILD). They were involved from 2011 to 2016, supporting clinical studies, genomic investigations, and FDA submissions for Sofosbuvir, its successor Harvoni/Ledipasvir and Sofosbuvir. - Clinical Trial: A phase I study was conducted using an individualized, heterologous chimpanzee adenovirus and self-amplifying mRNA neoantigen vaccine for advanced metastatic solid tumors. Interim results showed decreased circulating tumor DNA (ctDNA) in patients with prolonged overall survival (OS). - Methodology: Cell-free DNA (cfDNA) was isolated from the entire plasma volume of a single draw using the Apostle MiniMax cfDNA Isolation kit by ApostleBio. - Publication: The phase I clinical study was published in Nature Medicine, involving a joint clinical team from Gritstone Oncology, Columbia University Medical Center, Mayo Clinic, Memorial Sloan Kettering Cancer Center (MSKCC), MD Anderson Cancer Center, and other institutions.
title	Apostle Lab CRO Services
description	Apostle Lab CRO Services
keywords	apostle, laboratory, study, phase, health, team, plasma, high, state, medical, isolation, services, public, trial, university, using, cost
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nslookup	A 50.63.143.238
created	2025-03-26
updated	2025-05-10
summarized	2025-05-10